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Topline Results of the Randomized Controlled Trial

Topline Results of the Randomized Controlled Trial

Hiroko H Dodge, Kexin Yu, Chao-Yi Wu, Patrick J Pruitt, Meysam Asgari, Jeffrey A Kaye, Benjamin M Hampstead, Laura Struble, Kathleen Potempa, Peter Lichtenberg, Raina Croff, Roger L Albin, Lisa C Silbert, the I-CONECT Team , Internet-Based Conversational Engagement Randomized Controlled Clinical Trial (I-CONECT) Among Socially Isolated Adults 75+ Years Old With Normal Cognition or Mild Cognitive Impairment: Topline Results, The Gerontologist, Volume 64, Issue 4, April 2024, gnad147, https://doi.org/10.1093/geront/gnad147

Wu CY, Yu K, Arnold SE, Das S, Dodge HH. Who Benefited Most from the Internet-Based Conversational Engagement RCT (I-CONECT)? Application of the Personalized Medicine Approach to a Behavioral Intervention Study. J Prev Alzheimers Dis. 2024;11(3):639-648. doi: 10.14283/jpad.2024.41. PMID: 38706280; PMCID: PMC11061034.

Yu K, Wu CY, Silbert LC, Kaye JA, Dodge HH. I-CONECT intervention effects on weekly time spent outside of home and social contacts among socially isolated older adults. Front Public Health. 2024 Dec 16;12:1429331. doi: 10.3389/fpubh.2024.1429331. PMID: 39737466; PMCID: PMC11683118.

Studies that utilized the I-CONECT data 

Explore these publications that used the I-CONECT data.

Pourramezan Fard A, Mahoor MH, Alsuhaibani M, Dodge HH. Linguistic-based Mild Cognitive Impairment detection using Informative Loss.Comput Biol Med. 2024 Jun;176:108606. doi: 10.1016/j.compbiomed.2024.108606. Epub 2024 May 14. PMID: 38763068.

Alsuhaibani M, Dodge HH, Mahoor MH. Mild cognitive impairment detection from facial video interviews by applying spatial-to-temporal attention module. Expert Syst Appl. 2024 Oct 15;252(Pt B):124185. doi: 10.1016/j.eswa.2024.124185. Epub 2024 May 10. PMID: 38881832; PMCID: PMC11174143. 

Poor FF, Dodge HH, Mahoor MH. A multimodal cross-transformer-based model to predict mild cognitive impairment using speech, language and vision. Comput Biol Med. 2024 Sep 26;182:109199. doi: 10.1016/j.compbiomed.2024.109199. Epub ahead of print. PMID: 39332117.

Sun J, Dodge HH, Mahoor MH. MC-ViViT: Multi-branch Classifier-ViViT to Detect Mild Cognitive Impairment in Older Adults Using Facial Videos. Expert Syst Appl. 2024 Mar 15;238(Pt B):121929. doi: 10.1016/j.eswa.2023.121929. Epub 2023 Oct 4. PMID: 39238945; PMCID: PMC11375964.

​Struble LM, Potempa K, Lichtenberg PA, Croff RL, Ellis A, Dodge HH. Including Socially Isolated Black, Older Old Adults (Aged 80 and Above) with and without Mild Cognitive Impairment in a Clinical Trial: Recruitment Strategies and Perspectives. J Multidiscip Healthc. 2023 Nov 28;16:3663-3673. doi: 10.2147/JMDH.S427946. PMID: 38046050; PMCID: PMC10693244.

Wu CY, Mattek N, Wild K, Miller LM, Kaye JA, Silbert LC, Dodge HH. Can changes in social contact (frequency and mode) mitigate low mood before and during the COVID-19 pandemic? The I-CONECT project. J Am Geriatr Soc. 2022 Mar;70(3):669-676. doi: 10.1111/jgs.17607. Epub 2021 Dec 13. PMID: 34881436; PMCID: PMC8904274.

Liu G, Xue Z, Zhan L, Dodge HH, Zhou J. Detection of Mild Cognitive Impairment from Language Markers with Crossmodal Augmentation. Pac Symp Biocomput. 2023;28:7-18. PubMed PMID: 36540960; PubMed Central PMCID: PMC9782729.

Tang F, Chen J, Dodge HH, Zhou J. The Joint Effects of Acoustic and Linguistic Markers for Early Identification of Mild Cognitive Impairment. Front Digit Health. 2021;3:702772. doi: 10.3389/fdgth.2021.702772. eCollection 2021. PubMed PMID: 35224534; PubMed Central PMCID: PMC8878676.

Hong J, Zhu Z, Yu S, Wang Z, Dodge H, Zhou J. Federated Adversarial Debiasing for Fair and Transferable Representations. KDD. 2021 Aug;2021:617-627. doi: 10.1145/3447548.3467281. Epub 2021 Aug 14. PubMed PMID: 35571559; PubMed Central PMCID: PMC9105979.

Tang F, Uchendu I, Wang F, Dodge HH, Zhou J. Scalable diagnostic screening of mild cognitive impairment using AI dialogue agent. Sci Rep. 2020 Mar 31;10(1):5732. doi: 10.1038/s41598-020-61994-0. PMID: 32235884; PMCID: PMC7109153.

Cerino ES, Hooker K, Goodrich E, Dodge HH. (2019). Personality moderates intervention effects on cognitive function: A 6-week conversation-based intervention. Gerontologist. May 21. pii: gnz063. doi: 10.1093/geront/gnz063. 

Dodge HH. (2018). Using technology to advance social health.  In Leonard Kaye and Clifford Singer, edit. Social Isolation in Later Life: Strategies for Bolstering Health and Well-Being. Chapter 10: P135-148. New York: Springer Publishing Company.  (book chapter).

Yu K, Wild K, Potempa K, Hampstead BM, Lichtenberg PA, Struble LM, Pruitt P, Alfaro EL, Lindsley J, MacDonald M, Kaye JA, Silbert LC, DodgeHH. The Internet-Based Conversational Engagement Clinical Trial (I-CONECT) in Socially Isolated Adults 75+ Years Old: Randomized Controlled Trial Protocol and COVID-19 Related Study Modifications. Front Digit Health. 2021 Aug 25;3:714813. doi: 10.3389/fdgth.2021.714813. PMID: 34713183; PMCID: PMC8521795.

Chen J, Ye J, Tang F, Zhou J. Automatic Detection of Alzheimer's Disease Using Spontaneous Speech Only. Interspeech. 2021 Aug-Sep;2021:3830-3834. doi: 10.21437/interspeech.2021-2002. PubMed PMID: 35493062; PubMed Central PMCID: PMC9056005.

Yu S, Zhu Z, Liu B, Jain AK, Zhou J. Robust Unsupervised Domain Adaptation from A Corrupted Source. Proc IEEE Int Conf Data Min. 2022 Nov-Dec;2022:1299-1304. doi: 10.1109/icdm54844.2022.00171. Epub 2023 Feb 1. PubMed PMID: 37057074; PubMed Central PMCID: PMC10097501.

Asgari M, Kaye J, Dodge H. Predicting mild cognitive impairment from spontaneous spoken utterances. Alzheimers Dement (N Y). 2017 Feb 27;3(2):219-228. doi: 10.1016/j.trci.2017.01.006. PMID: 29067328; PMCID: PMC5651423.

Dodge HH, Mattek N, Gregor M, Bowman M, Seelye A, Ybarra O, Asgari M, Kaye JA. Social Markers of Mild Cognitive Impairment: Proportion of Word Counts in Free Conversational Speech. Curr Alzheimer Res. 2015;12(6):513-9. doi: 10.2174/1567205012666150530201917. PMID: 26027814; PMCID: PMC4526336.

Dodge HH, Zhu J, Mattek N, Bowman M, Ybarra O, Wild K, Loewenstein DA, Kaye JA. (2015). Web-enabled conversational interactions as a means to improve cognitive functions: Results of a 6-week randomized controlled trial. Alzheimers & Dementia : Translational Research and Clinical Interventions. 1(1): 1-12. PM26203461/PMC4507295

Dodge HH, Ybarra O, Kaye JA. (2014). Tools for advancing research into social networks and cognitive function in older adults.  International Psychogeriatrics. 26(4): 533-539. PM24152936/PMC3654367

Dodge HH, Katsumata Y, Zhu J, Mattek N, Bowman M, Gregor M, Wild K, Kaye JA. (2014). Characteristics associated with willingness to participate in a randomized controlled behavioral clinical trial using home-based personal computers and a webcam. Trials. 15: 508. PM25539637/PMC4307639

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